Division of Pulmonary, Critical Care & Sleep Medicine

Jinghong Li, M.D., Ph.d.

Assistant Adjunct Professor

 

CLINICAL INTERESTS:

Asthma
Interstitial Lung Disease
Lung Cancer

INVESTIGATIVE INTERESTS:
Innate immunity in inflammatory lung disease
Molecular mechanism of cystic and fibrotic lung disease
Novel therapeutic target in lung cancer

SELECTED PUBLICATIONS:

  • Grace Y. Lin, Kim M. Kerr, and Jinghong Li. Cough and Dyspnea: Thinking beyond Pneumonia. Ann Am Thorac Soc. 2013; in press.
  • Xiaoyu Hu, Pranabananda Dutta, Amy Tsurumi, Jinghong Li, Jingtong Wang, Hartmut Land, Willis X. Li. Unphosphorylated STAT5A stabilizes heterochromatin and suppresses tumor growth. Proc Natl Acad Sci U S A. 2013; 110(25):10213-8.
  • Jinghong Li, Ko-Wei Lin, Fiona Murray, Takeshi Nakajima, Yandong Zhao, David L. Perkins, and Patricia W. Finn. Regulation of cytotoxic T lymphocyte antigen 4 by cAMP. Am J Respir Cell Mol Biol. 2013; 48(1):63-70. Featured in “Red Alert”: Highlighted Papers by Junior Investigators.
  • Kriti Gaur, Jinghong Li, Dakun Wang, Amy Tsurumi, Hartmut Land, Guan Wu, and Willis X. Li. The Birt-Hogg-Dubé tumor suppressor negatively regulates ribosomal RNA. Hum. Mol. Genet. 2013;22(2):284-99.
  • Timothy M. Fernandez, Carmen Taype-Roberts, Jinghong Li. Venous thromboembolism prophylaxis, shorter courses of isoniazid for tuberculosis, and the microbiome in asthma. Am J Respir Crit Care Med 2012;186(3):286-7.
  • Jinghong Li, Andrew Yen, and Grace Y. Lin. Recurrent pneumonia, persistent cough and dyspnea a 41-Year Old Male. Chest. 2012;142(5):1338-42.
  • Jinghong Li, Gary Ewart, Monica Kraft, Patricia W. Finn. The Public Health Benefits of Air Pollution Control. J. Allergy Clin. Immunol. 2012;130(1):22-3.
  • Mark Goldin, Jinghong Li, Ali Amirrezvani, and David Riker. Pulmonary giant cell carcinoma associated with pseudomyxoma peritonei. J. Bronchol. Intervent. Pulmonol.  2012;19:50–53.
  • Ko-Wei Lin, Jinghong Li, and Patricia W. Finn. Emerging pathways in asthma: Innate and adaptive interactions. Biochim Biophys Acta. 2011;1810:1052-8.
  • Amy Tsurumi, Fan Xia, Jinghong Li, Kimberly Larson, Russell LaFrance, Willis X. Li. STAT Is an Essential Activator of the Zygotic Genome in the Early Drosophila Embryo.  PLoS Genet. 2011;7(5):e1002086.
  • Fan Xia, Jinghong Li, Gavin W. Hickey, Amy Tsurumi, Kimberly Larson, Dongdong Guo, Shian-Jang Yan, Louis Silver-Morse, Willis X. Li.  Raf activation is regulated by tyrosine 510 phosphorylation in Drosophila. PLoS Biol. 2008;6(5):e128.
  • Jinghong Li and Willis X. Li.  A novel function of Drosophila eIF4A as a negative regulator of Dpp/BMP signaling that mediates SMAD degradation. Nature Cell Biology 2006;8:1407-14. Featured in News and Views” by Editor.
  • Song Shi, Healeni C. Calhoun, Fan Xia, Jinghong Li, Long Le and Willis X. Li. JAK signaling globally counteracts heterochromatic gene silencing.  Nature Genetics 2006;38:1071-6.
  • Jinghong Li, Willis X. Li, and William M. Gelbart. A genetic screen for maternal effect suppressors of decapentaplegic identifies eukaryotic translation initiation factor 4A in Drosophila. Genetics 2005;171:1629-41.
  • Jinghong Li, Wenjun Li, Healani C. Calhoun, Fan Xia, Fen-Biao Gao and Willis X. Li. Patterns and functions of STAT activation during Drosophila embryogenesis.  Mech. Dev. 2003;120(12):1455-1468.
  • Jinghong Li, Fan Xia, and Willis X. Li. Coactivation of STAT and Ras is required for germ cell proliferation and invasive migration in Drosophila. Dev. Cell 2003;5:787-798.
  • Jinghong Li and Willis X. Li. Drosophila gain-of-function mutant RTK Torso triggers ectopic Dpp and STAT signaling. Genetics 2003;164: 247-258.
  • Jinghong Li, Kunikazu Tsuji, Toshihisa Komori, Kohei Miyazono, Jeffrey L. Wrana, Yoshiaki Ito, Akira Nifuji, and Masaki Noda. Smad2 overexpression enhances Smad4 gene expression and suppresses CBFA1 gene expression in osteoblastic osteosarcoma ROS17/2.8 cells and primary osteoblastic osteosarcoma. J. Biol. Chem. 1998;273(47):31009-31015.
  • Jinghong Li, Bing He, Baoying Weng. The therapeutic effect of TGF-beta monoclonal antibody to bleomycin-induced pulmonary fibrosis in rats. Chinese Journal of Tuberculosis and Respiratory Diseases. 1997;20:347-349.


HONORS AND AWARDS:

BOARD CERTIFICATION:

  • Internal Medicine
  • Pulmonary Disease

To contact Dr. Li: jinghongli@ucsd.edu