Division of Pulmonary & Critical Care Medicine

Demosthenes (Demos) Papamatheakis, M.D.

Clinical Instructor

 

SPECIAL CLINICAL INTERESTS

  1. Pulmonary Vascular Disease
  2. Critical Care Medicine


INVESTIGATIVE INTERESTS

  1. Pulmonary Vascular Contractility
  2. Pathophysiology of Pulmonary Hypertension


SELECTED PUBLICATIONS:

  1. Papamatheakis DG, et. al. Preservation of serotonin-mediated contractility in adult sheep pulmonary arteries following long-term high-altitude hypoxia. High Alt Med Biol. 2011 Fall;12(3):253-64.
  2. Goyal R, Papamatheakis DG, et. al. Long-term maternal hypoxia: the role of extracellular Ca2+ entry during serotonin-mediated contractility in fetal ovine pulmonary arteries. Reprod Sci. 2011 Oct;18(10):948-62.
  3. Merritt T, Papamatheakis DG, et. al. Rho-kinase and extracellular Ca2+ entry act synergistically to regulate serotonergic pulmonary arterial contractility in newborn lambs born at high altitude. (In preparation).
  4. Fansi AA, Papamatheakis DG, et. al. Racial variability of glaucoma risk factors between African Caribbeans and Caucasians in a Canadian urban screening population. Can J Ophthalmol. 2009 Oct;44(5):576-81
  5. Papamatheakis DG, et. al. Chronic angle closure glaucoma secondary to supra-choroidal effusion induced by central retinal vein occlusion. Ophthalmic Surg Lasers Imaging 2007 Mar-Apr;38(2):248-249.
  6. Harasymowycz PJ, Papamatheakis DG, et. al. Relationship between travoprost and central corneal thickness in ocular hypertension and open-angle glaucoma. Cornea. 2007 Jan;26(1):34-41.
  7. Harasymowycz PJ, Papamatheakis DG, et. al. Congenital Ectropion Uveae and Glaucoma. Arch Ophthalmol. 2006 Feb;124(2):271-3.
  8. Harasymowycz PJ, Papamatheakis DG, et. al. Validity of screening for glaucomatous optic nerve damage using confocal scanning laser ophthalmoscopy (Heidelberg Retina Tomograph II) in high-risk populations: a pilot study. Ophthalmology. 2005 Dec;112(12):2164-71.
  9. Harasymowycz P, Kamdeu Fansi A, Papamatheakis D. Screening for primary open-angle glaucoma in the developed world: are we there yet? Can J Ophthalmol. 2005 Aug;40(4):477-86. Review.
  10. Harasymowycz PJ, Papamatheakis DG, et. al. Selective laser trabeculoplasty (SLT) complicated by intraocular pressure elevation in eyes with heavily pigmented trabecular meshworks. Am J Ophthalmol. 2005 Jun;139(6):1110-3.
  11. Harasymowycz PJ, Papamatheakis DG, et. al. Phacoemulsification and goniosynechialysis in the management of unresponsive primary angle closure. J Glaucoma. 2005 Jun;14(3):186-9.
  12. Papamatheakis DG, et. al. Thrombocytopenia and the risks of intraocular surgery. Ophthalmic Surg Lasers Imaging. 2005 Mar-Apr;36(2):103-7.     
  13. Harasymowycz PJ, Papamatheakis DG. New Technologies in the Diagnosis and Monitoring of Glaucoma. Techniques in Ophthalmology 2004 Dec;2(4):142-54. Review.

 

HONORS/AWARDS

 

  1. ATS Fellows Track Symposium 2011 Travel Scholarship, FTS/ATS 2011, Denver, CO
  2. 2011 AFMR Henry Christian Award, ERAFMR Meeting 2011, Washington DC, DC
  3. 3rd Prize, Resident/Fellow Basic Science, Scientific Poster Session, 79th Alumni Postgraduate Conference 2011, LLU Medical School, Loma Linda, CA
  4. AFMR Scholar Award, WRAFMR Meeting 2011, Carmel, CA
  5. Finalist; 7th Annual Respiratory Disease Young Investigators’ Forum, San Antonio, TX\
  6. 2nd Prize, Resident/Fellow Basic Science, Scientific Poster Session, 78th Alumni Postgraduate Conference 2010, LLU Medical School, Loma Linda, CA
  7. Greek State Scholarship Foundation’s (IKY) Award for highest academic achievement (2003)
  8. Dretakis Award for academic excellence during Medical School senior year (2003)
  9. GlaxoSmithKline Scholarship for post- graduate research abroad (2003)

 

ABSTRACTS:

  1. 2011 American Thoracic Society International Conference, Denver, CO, USA (05/11) - (Poster presentation).Postnatal Maturation Decreases The Role Of Rho-Kinase In Electromechanical Coupling Of Sheep Pulmonary Arteries. D.G. Papamatheakis, et. al. Am J Respir Crit Care Med 183;2011:A5025
  2. Experimental Biology 2011, Washington DC, DC, USA (04/11) - (Poster presentation). Combined influence of ontogeny and chronic hypoxia on ryanodine receptor function in sheep pulmonary arteries and myocytes. S Hadley,Q Blood,P Le,DGPapamatheakis, et. al. FASEB J. 25:1034.8
  3. 2010 American Thoracic Society International Conference, New Orleans, LA, USA (05/10) - (Poster presentations). a. Maturation and chronic hypoxia influence alpha adrenergic function in the pulmonary vasculature of sheep. D.G. Papamatheakis, et. al. Am J Respir Crit Care Med 181;2010:A6280. b. Influence of postnatal maturity and chronic hypoxia on calcium activated chloride channels in pulmonary arterial vasoconstriction. S. Vemulakonda, M.D., D.G. Papamatheakis, MD, et. al. Am J Respir Crit Care Med 181;2010:A6278.
  4. Experimental Biology 2010, Anaheim, CA, USA (04/10) - (Poster presentations). a. In utero hypoxia augments hypoxic pulmonary vasoconstriction in newborn lamb. SM Wilson, DG Papamatheakis, et. al. FASEB J. 24: 1023.15 b. Synergism between Ca2+ and Rho-kinase signaling during pulmonary arterial vasoconstriction in chronic hypoxic newborn lamb. DG Papamatheakis, et. al. FASEB J. 24: 1023.16 c. RyR function in sheep pulmonary arteries is differentially influenced by postnatal maturation and chronic hypoxia. Q Blood, P Le, DG Papamatheakis, et. al. FASEB J. 24: 1061.4 d. Nonselective cation channel function in sheep pulmonary arteries is affected by postnatal maturation and chronic hypoxia. DG Papamatheakis, et. al. FASEB J. 24: 1061.8 e. The role of CaL in sheep pulmonary arteries is altered by chronic hypoxia and postnatal maturation. S Vemulakonda, DG Papamatheakis, et. al. FASEB J. 24: 1061.6 f. Functional interaction of ClCa with RyR and CaL in pulmonary arteries from chronic hypoxic sheep S Vemulakonda, DG Papamatheakis, et. al. FASEB J. 24: 1061.7 g. Muscarinic acetylcholine receptor dependent pulmonary arterial contractility is reduced by chronic hypoxia in fetal sheep. D Nguyen, DG Papamatheakis, et. al. FASEB J. 24: 1061.8
  5. Experimental Biology 2009, New Orleans, LA (04/09) – (Poster presentation). The role of calcium-activated chloride channels to serotonin-mediated pulmonary arterial tone is influenced by postnatal maturation. S Vemulakonda, J Angermann,K Vranken, DPapamatheakis, et. al. FASEB J. 23:999.1

Board Certification:

  • Internal Medicine
  • Pulmonary Disease
  • Critical Care Medicine

To schedule an appointment with Dr. Papamatheakis, contact 858-657-7100

To contact Dr. Papamatheakis: dpapamatheakis@ucsd.edu