Cooke, Jana R., M.D.

Clinical Instructor

VA Medical Center, San Diego

CLINICAL INTERESTS:

1. Sleep Medicine
2. Critical Care
3. Pulmonary Diseases

INVESTIGATIVE INTERESTS:

Sleep disturbance in the Critical Patient

SELECTED PUBLICATIONS:

1.     Rosenberg (Cooke) J.M., Perricone A, Savides T.J. EUS/FNA diagnosis of a malignant subcarinal lymph node in a patient with lung cancer and a negative PET scan.  Chest   122(3):1091-3, 2002.

2.     Cooke,J.R.  Emerging Concepts for Understanding Asthma. In:  The Respiratory Report, Martin RJ ed.  Direct One Communications, 2005.

3.     Ancoli-Israel,S. and Cooke,J.R.   Prevalence and co-morbidity of insomnia and impact on functioning in elderly populations.   Journal of American Geriatric Society, 53:S264-271, 2005.

4.     Cooke, J.R., Loredo J.S., Liu L., Marler M., Corey-Bloom J., Fiorentino L., Ancoli-Israel S.  Acetylcholinesterase inhibitors and sleep architecture in patients with Alzheimer’s disease.  Drugs and Aging, 23(6):503-511, 2006.

5.     Ayalon,L., Ancoli-Israel,S., Stepnowsky,C., Palmer,B.W., Liu,L., Loredo,J.S., Corey-Bloom,J., Greenfield,D., Cooke,J.R.   Treatment adherence in patients with Alzheimer's disease and obstructive sleep apnea.   American Journal of Geriatric Psychiatry   14(2):176-80, 2006.

6.     Cooke J.R., Liu L, Marler M, Loredo J.S., Greenfield D, Ancoli-Israel S.  The effect of sleep disordered breathing on sleep architecture in patients with Alzheimer’s disease. Behavioral Sleep Medicine, 4(4):219-27, 2006.

7.   Cooke J.R., Behling C.A., Perricone A., Savides T.J.  Using Trans-Esophageal Endoscopic Ultrasound-Guided Fine Needle Aspiration to Diagnose Sarcoidosis in Patients with Mediastinal Lymphadenopathy.  Clinical Pulmonary Medicine, 15(1):13-17, 2008.

8.  Cooke J.R. Sleep disorders in older adults. Psychiatric Times (invited review), 25(4),  2008.

Book Chapters

1.     Cooke,J.R. and Catanzaro A. Crytptococcosis and Actinomycosis.  In:  Bordow RA, Ries AL, Morris TA (eds.)  Manual of Clinical Problems in Pulmonary Medicine,. 6th edition.  Lippincott Williams and Wilkins, 2005.

2.     Cooke,J.R. and Catanzaro A. Nontuberculous Mycobacteria. In:  Bordow RA, Ries AL, Morris TA (eds.)  Manual of Clinical Problems in Pulmonary Medicine, 6th edition.  Lippincott Williams and Wilkins, 2005.    

3.     Cooke,J.R. and Ancoli-Israel,S.   Sleep-related breathing disorders in the elderly. In: Randerath,W.J., Sanner,B.M. and Somers,V.K. (eds.)  Sleep Apnea - Current Diagnosis and Treatment.   Basel, Switzerland:   Karger, 2005.        

4.     Cooke,J.R. and Ancoli-Israel,S.   Normal and abnormal sleep in the elderly. In: Montagna,P. and Chokroverty,S. (eds.)  Handbook of Clinical Neurology: Sleep Disorders.   Elsevier, 2006.

5.     Cooke, J.R. and Ancoli-Israel,S.  Sleep and its disorders in older adults. In: Doghramji,K. (ed.)  Psychiatric Clinics of North America. Elsevier, 2006.

6.   Cooke, J.R. and Ancoli-Israel,S. Geriatric Psychiatry: Sleep Disorders. In: Sadock,B.J., Sadock,V.A., Ruiz,P. (eds.)  Kaplan and Sadock’s Comprehensive Textbook of Psychiatry, 9th edition.  Lippincott Williams & Wilkins, 2010.

7.   Cooke, J.R. and Ancoli-Israel, S. Assessment and differential diagnosis of sleep disorders in the elderly. In: Pandi-Perumal, Monti, and Monjan (eds.) Principles & Practice of Geriatric Sleep Medicine. 1st edition. Cambridge University Press, 2008.

Abstracts

1.     Rosenberg (Cooke) J.M., Behling C, Perricone A, Savides T.J. Diagnosis of mediastinal lymph node granulomas in patients with suspected sarcoidosis using trans-esophageal endoscopic ultrasound-guided fine needle aspiration.  American College of Gastroenterology annual meeting, 2001.

2.     Rosenberg (Cooke) J.M., Perricone A, Savides T.J. EUS/FNA diagnosis of a malignant subcarinal lymph node in a patient with lung cancer and a negative PET scan.  American College of Gastroenterology annual meeting, 2001.

3.     Cooke,J.R., Liu,L., Marler,M., Ancoli-Israel,S.   Sleep Architecture in Alzheimer's Disease Patients With and Without Sleep-Disordered Breathing.  Proceedings of the American Thoracic Society, 2:A760, 2005.

4.     Cooke,J.R., Liu,L., Marler,M., Fiorentino,L., Amador,X., Ancoli-Israel,S.   Sleep disordered breathing lightens sleep but does not increase awakenings in patients with Alzheimer's disease.  Sleep, 28:A109-110, 2005.

5.     Cooke,J.R., Loredo,J.S., Liu,L., Marler,M., Greenfield,D., Amador,X., Ancoli-Israel,S.   The effect of acetylcholinesterase inhibitors on sleep architecture in patients with Alzheimer's disease.  Sleep, 28:A114, 2005.

6.  Cooke, J.R., Amador, X., Lawton, S., Greenfield, D., Liu, L., Marler, M., Palmer, B., Ancoli-Israel, S.  Long-term CPAP may improve cognition, sleep, and mood in patients with Alzheimer’s disease and SDB.  Sleep, 29:A308, 2006.

7.   Bartolome, S.D., Channick, R.L., Williamson, T.L., Cooke, J.R., Kim, H., Stites, S.W., Rubin, L.J.  Low-dose dopamine infusion as outpatient therapy for pulmonary arterial hypertension patients failing intravenous epoprostenol.  Proceedings of the American Thoracic Society, 3:A418, 2006.

8.     Ancoli-Israel, S., Liu, L., Cooke, J.R., Fiorentino, L., Parker, B., Natarajan, L.  Fatigue, depression and poor sleep before chemotherapy in women with breast cancer result in worse outcome.  Sleep Medicine, 8(1):S509, 2007.

9.  Cooke, J.R., Loredo, J.S., Ancoli-Israel, S., Davidson, T. Effectiveness of Treatment for Obstructive Sleep Apnea Based on Unattended Home Evaluation.  American Journal of Respiratory and Critical Care Medicine, 175:A707, 2007.

10.  Cooke, J.R., Liu L., Fiorentino L., Lawton S., Corey-Bloom J., Loredo J.S., Palmer B.W., Natarajan L., He F., Ancoli-Israel S. CPAP improves sleep in patients with Alzheimer’s disease and sleep disordered breathing. Sleep, 30:A307, 2007.

11. Cooke J.R., Liu L., Neikrug A., Corey-Bloom J., Loredo J.S., Palmer B.W., He, F., Natarajan L., Ancoli-Israel S. Increase in Total Sleep Time is Associated with Improvements in Cognition in Alzheimer's Disease Patients Treated for OSA. Sleep, TBA, 2008.

PRESENTATIONS

1.     Acute Respiratory Distress Syndrome.  Grossmont College Respiratory Therapy Department, October 2003 

2.     The Effect of Acetylcholinesterase Inhibitors on Sleep Architecture in Patients with Alzheimer's disease. 19th Annual Meeting of the Association of Professional Sleep Societies.  Sleep Research Society Trainee Day. Denver, CO. June 19, 2005 

3.     ICU Delirium.  University of California San Diego Critical Care Summer Session.  San Diego, CA.  July 22, 2005.

4.     ICU Delirium.  University of California San Diego Medical Center, CME Course.  San Diego, CA. July 25, 2005.

5.     Is Sedation Keeping Patients on the Ventilator Longer? University of California San Diego, Respiratory Care Department. 7th Annual Mechanical Ventilator Conference.  San Diego, CA.  March 5, 2006.

6.     ICU Delirium and the CAM-ICU. University of California San Diego Medical Center. CME Course.  San Diego, CA. March 8, 2006.

7.   ICU Delirium and the CAM-ICU.  University of California San Diego Medical Center, Thornton Hospital.  CME course.  La Jolla, CA.  April 24, 2006.

8. Sedation, Ventilators and Delirium. University of California San Diego Critical Care Summer Session.  San Diego, CA.  July 21, 2006.             

 9.   Effect of CPAP on Sleep and Cognition in Patients with Alzheimer’s Disease and Sleep Apnea.  Shiley-Marcos Alzheimer’s Disease Research Center Data Blitz, La Jolla, CA.  November 13, 2007.          

10. Sedation, Delirium, and Ventilators. University of California San Diego, Advances in Internal Medicine Mechanical Ventilator Conference.  San Diego, CA.  March 9, 2008.

11. Sleep Apnea and Congestive Heart Failure. The San Diego Heart Failure Foundation’s 14th San Diego Annual Heart Failure Symposium. La Jolla, CA. May 3, 2008.

12. Increase in Total Sleep Time is Associated with Improvements in Cognition in Alzheimer's Disease Patients Treated for OSA.  22nd Annual Meeting of the Association of Professional Sleep Societies. Baltimore, MD. June 10, 2008

Honors and Awards:

2008                    Sleep Research Society’s Honorable Mention Abstract award

2005                    Sleep Research Society’s Trainee Merit Based Travel Award

1997-9                 Dean’s Scholar Junior/Senior Continuum

1996-7                 Association of Pathology Chairs (APC) Pathology Honor Society

JOURNAL REVIEWER

• American Journal of Geriatric Psychiatry

• Behavioral Sleep Medicine

• Geriatrics

• Sleep Medicine

• UC Berkeley Wellness Letter

PubMed

Board Certified:

  Internal Medicine

  Pulmonary Medicine

  Critical Care Medicine

  Sleep Medicine

VA Medical Center

For further information, contact Jrcooke@ucsd.edu