Research

Our Focus

The Center specifically focuses on important but understudied questions regarding human responses to low oxygen, including:

• how variation is distributed among different ancestral groups,
• how this variation influences or reflects system-wide differences in oxygen transport, and
• how these differences ultimately contribute to distinct responses to low oxygen (hypoxia) inherent to many common disease states.

Genomic and systems-level physiological and molecular data collected and analyzed through separate but highly integrated components of the center aim to address these concerns at basic and clinical research levels.