Publications

Darquenne C., Borja M.G., Oakes J.M., Breen E.C., Olfert I.M., Scadeng M., Prisk G.K. Increase in relative deposition of fine particles in the rat lung periphery in the absence of gravity. J Appl Physiol., 117(8):880-6, 2014. [ PubMed ]

Darquenne, C. Aerosol Deposition in the Human Lung in Reduced Gravity. J Aerosol Med Pulm Drug Deliv., 27(3): 170-177, 2014. [ PubMed ]

Prisk G.K. Microgravity and the respiratory system. Eur Respir J., 43(5):1459-71, 2014. [ PubMed ]

Prisk G.K., Sá R.C., Darquenne C. Cardiogenic mixing increases aerosol deposition in the human lung in the absence of gravity.Acta Astronaut., 92(1):15-20, 2013. [ PubMed ]

Darquenne C., Zeman K.L., Sá R.C., Cooper T.K., Fine J.M., Bennett W.D., Prisk G.K. Removal of sedimentation decreases relative deposition of coarse particles in the lung periphery.J. Appl. Physiol., 115(4):546-55, 2013. [ PubMed ]

Darquenne C., Prisk G.K. Particulate deposition in the human lung under lunar habitat conditions.Aviat Space Environ Med. 84(3):190-5, 2013. [ PubMed ]

Prisk G.K. Microgravity.Comprehensive Physiol., 1(1):485-97, 2011. [ PubMed ]

Prisk G.K. Gas exchange under altered gravitational stress.Comprehensive Physiol. 1(1):339-55, 2011. [ PubMed ]

Prisk G.K. Pulmonary circulation in extreme environments. Comprehensive Physiol. 1(1):319-38, 2011. [ PubMed ]

Sá R.C., Prisk G.K., Paiva M. Microgravity alters respiratory abdominal and rib cage motion during sleep. J. Appl. Physiol., 107(5):1406-12, 2009. [ PubMed ]

Prisk G.K., Fine J.M., Cooper T.K., West J.B. Lung function is unchanged in the 1 G environment following 6-months exposure to microgravity.Eur J Appl Physiol., 103(6):617-23, 2008. [ PubMed ]

Darquenne C., Prisk G.K. Deposition of inhaled particles in the human lung is more peripheral in lunar than in normal gravity. Eur J Appl Physiol., 103(6):687-95, 2008. [ PubMed ]

Hughes, M., J.B. West.. Point:Counterpoint : Gravity is/is not the major factor determining the distribution of blood flow in the human lung. J. Appl. Physiol., 2008 May 1; 104(5), 1531-1533. [ PubMed ]

Prisk G.K., Fine J.M., Cooper T.K., West J.B. Vital capacity, respiratory muscle strength, and pulmonary gas exchange during long-duration exposure to microgravity.J. Appl. Physiol., 101(2):439-47, 2006. [ PubMed ]

Prisk G.K., Fine J.M., Cooper T.K., West J.B. Pulmonary gas exchange is not impaired 24 h after extravehicular activity.J. Appl. Physiol., 99(6):2233-8, 2005. [ PubMed ]

Prisk G.K. The lung in space. Clinics in Chest Med. 2005 Sep; 26(3):415-38, vi. [ PubMed ]

Dutrieue B., Verbanck S., Darquenne C., Prisk G.K. Airway closure in microgravity. Respir Physiol Neurobiol. 2005 Aug 25; 148(1-2):97-111. [ PubMed ]

Darquenne, C. and G.K. Prisk. Effect of small flow reversals on aerosol mixing in the alveolar region of the human lung. J. Appl Physiol., 97(6): 2083-9, 2004. [ PubMed ]

Darquenne, C. and G.K. Prisk. Effect of gravitational sedimentation on simulated aerosol dispersion in the human acinus. J. Aerosol Sci., 34(4):405-418, 2003. [ PubMed ]

Dutrieue, B., M. Paiva, S. Verbanck, M. Le Gouic, C. Darquenne and G. Kim Prisk. Tidal volume single breath washin of SF₆ and CH₄ in transient microgravity. J. Appl. Physiol., 94(1):75-82, 2003. [ PubMed ]

Darquenne, C. Heterogeneity of aerosol deposition in a two-dimensional model of human alveolated airways. J. Aerosol Sci., 33:1261-1278, 2002.

Prisk G.K., Fine J.M., Elliott A.R., West J.B.. Effect of 6 degrees head-down tilt on cardiopulmonary function: comparison with microgravity. Aviat Space Environ Med. 2002 Jan; 73(1):8-16. [ PubMed ]

G.K. Prisk, M.Paiva, and J.B. West (eds.) Gravity and the lung: Lessons from microgravity. New York, NY, Marcel Dekker, Inc., 2001.

Darquenne, C. Aerosol transport in the lung. In: Gravity and the lung: Lessons from microgravity. Prisk GK, Paiva M, West JB, editors. New York, NY, Marcel Dekker, Inc., 2001.

Paiva, M. and Prisk, G.K. Ventilation distribution. In: Gravity and the lung: Lessons from microgravity. Prisk GK, Paiva M, West JB, editors .New York, NY, Marcel Dekker, Inc., 2001.

Prisk, G.K. Control of ventilation. In: Gravity and the lung: Lessons from microgravity. Prisk GK, Paiva M, West JB, editors. New York, NY, Marcel Dekker, Inc., 2001.

Prisk, G.K. Pulmonary perfusion: gravitational components. In: Gravity and the lung: Lessons from microgravity. Prisk GK, Paiva M, West JB, editors. New York, NY, Marcel Dekker, Inc., 2001.

West, J.B. Pulmonary gas exchange. In: Gravity and the lung: Lessons from microgravity. New York, NY, Marcel Dekker, Inc., 2001.

Dijk D.J., Neri D.F., Wyatt J.K., Ronda J.M., Riel E., Ritz-De Cecco A., Hughes R.J., Elliott A.R., Prisk G.K., West J.B., Czeisler C.A. Sleep, performance, circadian rhythms, and light-dark cycles during two space shuttle flights.Am J Physiol Regul Integr Comp Physiol. 2001 Nov; 281(5):R1647-64. [ PubMed ]

Elliott, A.R., S.A. Shea, D-J. Dijk, J.K. Wyatt, E. Riel, D.F. Neri, C.A. Cziesler, J.B. West, and G.K. Prisk. Microgravity reduces sleep-disordered breathing in humans. Am. J. Respir. Crit. Care Med. 164:478-485, 2001. [ PubMed ]

Darquenne, C. A realistic two-dimensional model of aerosol transport and deposition in the alveolar zone of the human lung. J. Aerosol Science 32:1161-1174, 2001.

Y. Verbandt, M. Wantier, G. K. Prisk, and M. Paiva. Ventilation-perfusion matching in long-term microgravity. J. Appl. Physiol. 89(6): 2407-2412, 2000. [ PubMed ]

Darquenne, C., M. Paiva, and G.K. Prisk. Effect of gravity on aerosol dispersion and deposition in the human lung after periods of breath holding. J. Appl. Physiol. 89(5): 1787-1792, 2000. [ PubMed ]

Prisk, G.K. Microgravity and the Lung. J. Appl. Physiol. Invited Review, 89(1):385-396, 2000. [ PubMed ]

Prisk, G.K., A.R. Elliott, and J.B. West. Sustained microgravity reduces the human ventilatory response to hypoxia but not to hypercapnia. J. Appl. Physiol. 88(4):1421-1430, 2000. [ PubMed ]

West, J.B. and G.K. Prisk. Chest volume and shape and intrapleural pressure in microgravity. J. Appl. Physiol. 87(3):1240-1241, 1999. [ PubMed ]

Dutrieue, B., A.-M. Lauzon, S. Verbanck, A.R. Elliott, J.B. West, M. Paiva, and G.K. Prisk. Helium and sulfur hexafluoride bolus washin in short-term microgravity. J. Appl. Physiol. 86(5):1594-1602, 1999. [ PubMed ]

Darquenne, C., J.B. West, and G.K. Prisk. Dispersion of 0.5- to 2-µm aerosol in µG and hypergravity as a probe of convective inhomogeneity in the lung. J. Appl. Physiol. 86(4):1402-1409, 1999. [ PubMed ]

Darquenne, C., J.B. West, and G.K. Prisk. Deposition and dispersion of 1-µm aerosol boluses in the human lung: effect of micro- and hypergravity. J. Appl. Physiol. 85(4):1252-1259, 1998. [ PubMed ]

Prisk, G.K. Gravity and lung function. The Physiological Society Magazine 33:16-18, 1998.

Prisk, G.K. Sleep and respiration in microgravity. Neuroscience News 1(5):39-45, 1998. [ PubMed ]

Elliott, A.R., G.K. Prisk, C. Schollman, and U. Hoffmann. Part Two: Hypercapnic ventilatory response in humans before, during and after 23 days of low-level CO2 exposure. Aviat. Space and Environ. Med. 69:391-396, 1998. [ PubMed ]

Wantier, M., M. Estenne, S. Verbanck, G.K. Prisk, and M. Paiva. Chest wall mechanics in sustained microgravity. J. Appl. Physiol. 84(6):2060-2065, 1998. [ PubMed ]

Lauzon, A.-M., A.R. Elliott, M. Paiva, J.B. West, and G.K. Prisk. Cardiogenic oscillation phase relationships in normal gravity and microgravity. J. Appl. Physiol. 84(2):661-668, 1998. [ PubMed ]

Prisk, G. Kim, A.R. Elliott, H.J.B. Guy, S. Verbanck, M. Paiva, and J.B. West. Multiple-breath washin of helium and sulfur hexafluoride in sustained microgravity. J. Appl. Physiol. 84(1): 244-252, 1998. [ PubMed ]

Darquenne, C., M. Paiva, J.B. West, and G.K. Prisk. Effect of microgravity and hypergravity on deposition of 0.5- to 3-um diameter aerosol in the human lung. J. Appl. Physiol. 83(6):2029-2036, 1997. [ PubMed ]
West, J.B., A.R. Elliott, H.J.B. Guy, and G.K. Prisk. Pulmonary function in space. JAMA. 277:1957-1961, 1997. [ PubMed ]

Verbanck, S., H. Larsson, D. Linnarsson, G.K. Prisk, J.B. West, and M Paiva. Pulmonary tissue volume, cardiac output, and diffusing capacity in sustained microgravity. J. Appl. Physiol. 83(3):810-816, 1997. [ PubMed ]

Lauzon, A.-M., G.K. Prisk, A.R. Elliott, S. Verbanck, M. Paiva, and J.B. West. Paradoxical helium and sulfur hexafluoride single-breath washouts in short-term vs. sustained microgravity. J. Appl. Physiol. 82(3):859-865, 1997. [ PubMed ]

West, J.B., H.J.B Guy, A.R. Elliott, and G.K. Prisk. Respiratory system in microgravity. In: Handbook of Physiology, Section 4: Environmental Physiology. M.J. Fregly and C.M. Blatteis (eds.). New York, Oxford University Press. pp. 675-689, 1996.

Elliott, A.R., G.K. Prisk, H.J.B. Guy, J.M. Kosonen, and J.B. West. Forced expirations and maximum expiratory flow-volume curves during sustained microgravity on SLS-1. J. Appl. Physiol. 81:33-43, 1996. [ PubMed ]

Verbanck, S., D. Linnarson, G.K. Prisk, and M. Paiva. Specific ventilation distribution in microgravity. J. Appl. Physiol. 80:1458-1465, 1996.

Prisk, G.K., A.-M. Lauzon, S. Verbanck, A.R. Elliott, H.J.B. Guy, M. Paiva, and J.B. West. Anomalous behavior of helium and sulfur hexafluoride during single-breath tests in sustained microgravity. J. Appl. Physiol. 80:1126-1132, 1996. [ PubMed ]

Verbanck, S., G. K. Prisk, H.J.B. Guy, J.B. West, L. A. Engel, and M. Paiva. Ventilation distribution and chest wall mechanics in microgravity. In: Proceedings of the Norderney Symposium on Scientific Results of the German Spacelab Mission D-2. P.R. Sahm, M.H. Keller, B. Schiewe (eds). Köln, Germany, Wissenschaftliche Projektführung D-2. Pp. 754-759, 1995.

Prisk, G.K., A.R. Elliott, H.J.B. Guy, J.M. Kosonen, and J.B. West. Pulmonary gas exchange and its determinants during sustained microgravity on Spacelab SLS-1 and SLS-2. J. Appl. Physiol. 79(4):1290-1298, 1995. [ PubMed ]

Prisk, G.K., A.R. Elliott, and J.B. West. Flexible automated pulmonary function testing--experience from Spacelab. In: Proceedings, Life Sciences and Space Medicine Conference '95, Houston TX, AIAA, April 3-5, 1995, p. 43-44.

Prisk, G.K., H.J.B. Guy, A.R. Elliott, M. Paiva, and J.B. West. Ventilatory inhomogeneity determined from multiple-breath washouts during sustained microgravity on Spacelab SLS-1. J. Appl. Physiol. 78:597-607, 1995. [ PubMed ]

Elliott, A.R., G.K. Prisk, H.J.B. Guy, and J.B. West. Lung volumes during sustained microgravity on Spacelab SLS-1. J. Appl. Physiol. 77(4):2005-2014, 1994. [ PubMed ]

Prisk, G.K., H.J.B. Guy, A.R. Elliott, and J.B. West. Inhomogeneity of pulmonary perfusion during sustained microgravity on SLS-1. J. Appl. Physiol. 76:1730-1738, 1994. [ PubMed ]

Guy, H.J.B, G.K. Prisk, A.R. Elliott, R.A. Deutschman III, and J.B. West. Inhomogeneity of pulmonary ventilation during sustained microgravity as determined by single-breath washouts. J. Appl. Physiol.. 76:1719-1729, 1994. [ PubMed ]

Prisk,G.K., H.J.B. Guy, A.R. Elliott, R.A. Deutschman III, and J.B. West. Pulmonary diffusing capacity, capillary blood volume, and cardiac output during sustained microgravity. J. Appl. Physiol. 75:15-26, 1993. [ PubMed ]

Guy H.J., Prisk G.K., West J.B. Pulmonary function in microgravity. Physiologist, 35 (1 Suppl):S99-102, 1991. [ PubMed ]

West J.B. Microgravity and the lung.Physiologist, 34(1 Suppl):S8-10, 1991. [ PubMed ]

West J.B. Human experiments on Spacelab SLS-1. Physiologist, 34(1 Suppl):S27-8, 1991. [ PubMed ]

Guy, H.J.B., G.K. Prisk, A.R. Elliott, and J.B. West. Maximum expiratory flow-volume curves during short periods of microgravity. J. Appl. Physiol. 70:2587-2596, 1991. [ PubMed ]

Guy, H.J.B. and G.K. Prisk. Heart-lung interactions in aerospace medicine. In Heart-Lung Interactions in Health and Disease. Vol. 42, eds. S.M. Scharf and S.S. Cassidy. New York, NY, Marcel Dekker, Inc., pp. 519-563, 1989. [ NASA Tech Report ]

Guy, H.J.B., G.K. Prisk, and J.B. West. Pulmonary function in microgravity: Spacelab 4 and beyond. Acta Astronautica. 17(10): 1139-1143, 1988. [ PubMed ]